Ginkgoselect® overview
Clinical studies

Ginkgoselect® Phytosome®

Bioavailable standardized extract of Ginkgo biloba leaves

Although the medicinal properties of Ginkgo biloba L. have been known in China since the most ancient times, a systematic pharmacological and clinical study of this plant only began in Europe in the last decades(1).
Often defined as a “living fossil”, the Ginkgo biloba tree is the only survivor of a genus originated 150 millions years ago. It derives its name from a wrong transcription of the Japanese Yin-Kwo, meaning “silver fruit”.
In an extensive review by DeFeudis(2) in 1991, the activity of Ginkgo biloba is describred as “polyvalent”, as its pharmacological action is due to the combined activity of several actives.
The major therapeutic indications for the standardized Ginkgo biloba leaves extract concern cerebral insufficiency and peripheral vascular disorders(1).
The term “cerebral insufficiency” indicates a collection of symptoms concerning the cerebral functions, such as impairment of short term memory, confusion, change in social behavior, lack of initiative, affective and somatic troubles. These symptoms may be associated with impaired cerebral circulation and ageing.
Considered as early signs of senile dementia both of degenerative type and vascular origin, the symptoms are treated with Ginkgo biloba extract (GBE) which is considered a drug of choice in the growing area of senile dementia.

A natural cognition enhancer

The cognition enhancing properties of the plant are attributed to the flavonoids fraction which are responsible for:

The unique terpenoids ginkgolides and bilobalide exert vaso- and tissue-protective activity as:

The content of GBE

≥ 24% of ginkgoflavonglucosides
≥ 6% of ginkgolides and bilobalide
≤ 5 ppm of ginkgoic acids

To further improve its bioavailability, GBE has been complexed with soy (non-GMO) phospholipids (1:2 w/w), thus obtaining Ginkgoselect® Phytosome®.
Pharmacokinetic data on human volunteers support the bioavailability improvement in Ginkgoselect® Phytosome®, while its activity is supported by clinical trials(3,4) with pharmacokinetic(5,6) and pharmacological data(1,8).

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